I'm bootstrapping out of Bangkok, Thailand (I'm Swiss). Not really a digital nomad anymore, as I'm kinda settled at the moment. It's got it's fair share of advantages and disadvantages.
Disadvantage: Timezone difference to US is huge +/- 12h (to Europe however it's very convenient especially if you hate getting up early), internet is fast enough but there is a noticeably lag, Visa situation requires you to travel out every once in a while, but i quite like these enforced holidays.
Bangkok is quite a modern city, so you can find anything you want, food, crossfit gyms, great coffee, beers, international food. Transportation is ok if you can manage when and where to travel (unlike normal office-worker expats here).
Advantages are that it's quick to get setup, arrive here and within 1-2 days get a nice fully-furnished appartment on short term rental lease, co-working places, 3g, internet and everything else you need. You can outsource every mundane task for little money, cleaning, laundry service, cooking (eating out is cheap). Budgets: Below 1000$ it's doable but hard (IMO also for middle-class thais). Realistically 1K$ for bootstrapping/ramen-profitable, 2000-3000$ for a good lifestyle, and for 4000-5000$ you live like a king. Other niceties of living in Bangkok is close proximity to the whole area, especially singapore and its many tech and startup events.
Interesting observation is that living in a place where things do break down gets you into a mindset of planning well ahead and setting up your systems to be more fault-tolerant. So setting up servers and human processes in a way that they can function without me become a priority.
To sum up, you can live a very nice lifestyle here for a lot less, vastly superior to the west in my opinion. I see it like with uptime SLAs, Europe/US gives you a 99.9% reliability of infrastructure and bangkok 99% which makes everything cheaper (and more exciting) but you need to adapt.
If you have any questions, feel free to ask or send PM.